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Extraintestinal cancers in Crohn's disease
H Nakajima1, A Munakata, Y Yoshida
1First Department of Internal Medicine, Hirosaki University School of Medicine, Japan.
Digestion
|January 1, 1990
Summary
Patients with Crohn's disease (CD) have an increased risk of developing extraintestinal cancers, particularly genitourinary tumors. Vigilance for these cancers is crucial in CD patient care.
Area of Science:
- Gastroenterology
- Oncology
Background:
- Crohn's disease (CD) is a chronic inflammatory condition.
- Extraintestinal manifestations are common in CD.
Observation:
- Four cases of extraintestinal cancer were observed in CD patients: renal, urinary bladder, ovarian, and myeloma.
- Literature review identified 75 additional cases of extraintestinal cancer complicating CD.
Findings:
- A significant association exists between Crohn's disease and extraintestinal cancers.
- Genitourinary tumors appear to be a notable risk in CD patients.
Implications:
- Clinicians should maintain a high index of suspicion for extraintestinal cancers in CD patients.
- Further research is needed to determine the causal relationship between CD and these cancers.