Related Experiment Video
Updated: May 19, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
Laugier-Hunziker syndrome.
Ramakant S Nayak1, Vijayalakshmi S Kotrashetti, Jagadish V Hosmani
1Department of Oral Pathology and Microbiology, Maratha Mandal's NG Halgekar Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India.
Laugier-Hunziker syndrome is a rare benign condition causing oral and nail pigmentation. Prompt recognition is key to differentiate it from other disorders requiring medical intervention.
Area of Science:
- Dermatology
- Oral Medicine
- Genetics
Background:
- Laugier-Hunziker syndrome is a rare acquired disorder.
- Characterized by oral mucosal hyperpigmentation and longitudinal melanonychia.
- Considered benign with no systemic or malignant potential.
Purpose of the Study:
- To review Laugier-Hunziker syndrome.
- Discuss its differential diagnosis.
- Highlight the importance of prompt clinical recognition.
Main Methods:
- Literature review on Laugier-Hunziker syndrome.
- Analysis of differential diagnoses for mucocutaneous pigmentary disorders.
Main Results:
- Laugier-Hunziker syndrome presents as macular lesions (<5 mm).
- It is crucial to distinguish from other conditions requiring medical management.
- Few cases reported in India.
Conclusions:
- Early identification of Laugier-Hunziker syndrome avoids unnecessary procedures.
- Distinguishing it from other pigmentary disorders is essential.
- Further case reporting from India is warranted.
Related Concept Videos
Huntington Disease l: Introduction
Lysosomal Hydrolases
Horney's Sociocultural Approach
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Esophageal Achalasia
