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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
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Primary Symptoms of COPD:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

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Related Experiment Video

Updated: May 19, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
04:33

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Sinusitis and chronic cough in children.

Nevin W Wilson1, Mary Beth Hogan, Charles Bruce Harper

  • 1University of Nevada School of Medicine, Department of Pediatrics, Section of Allergy, Immunology and Pulmonology, Reno, NV, USA.

Journal of Asthma and Allergy
|August 28, 2012
PubMed
Summary

Sinus X-rays can help diagnose chronic cough in children. Abnormalities were found in 65% of children with coughs lasting over 4 weeks, suggesting X-rays are useful screening tools.

Keywords:
Water’s view sinus X-rayallergic rhinitisasthmapost-tussive emesisradiologistwheezing

Related Experiment Videos

Last Updated: May 19, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
04:33

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Area of Science:

  • Pediatric Pulmonology
  • Pediatric Radiology
  • Medical Diagnostics

Background:

  • Chronic cough is a frequent pediatric concern, often linked to sinusitis.
  • Diagnosing sinusitis in children typically relies on clinical assessment, with CT scans often preferred over sinus X-rays for confirmation.

Purpose of the Study:

  • To determine the prevalence of abnormal sinus X-rays in children experiencing chronic cough (>4 weeks).
  • To compare sinus X-ray interpretations between allergy/pulmonary specialists and radiologists.
  • To correlate clinical symptoms with X-ray findings in pediatric chronic cough cases.

Main Methods:

  • A retrospective chart review was conducted on 86 pediatric patients (ages 2-18) with cough duration exceeding 4 weeks.
  • Data included clinical evaluations, Water's view sinus X-ray results, and patient outcomes.
  • Statistical analyses were performed to assess associations between symptoms and X-ray findings.

Main Results:

  • Clinicians identified abnormal sinus X-rays in 65% of cases, closely aligning with radiologists' findings (62%).
  • Positive X-ray results showed significant correlations with post-tussive emesis and purulent nasal discharge.
  • Sinus X-ray abnormalities were strongly associated with most clinical findings, excluding wheezing.

Conclusions:

  • Sinus abnormalities detected via X-ray are present in 65% of children with chronic cough.
  • The Water's view sinus X-ray serves as a valuable initial screening tool for clinicians managing pediatric chronic cough.
  • Specific physical signs and symptoms, when occurring together, correlate well with abnormal sinus X-ray findings.