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Myocardial infarction in a patient with left ventricular noncompaction: a case report
Mehrnoush Toufan1, Roya Shahvalizadeh, Majid Khalili
1Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
Left ventricular noncompaction (LVNC) is associated with myocardial infarction (MI) and coronary artery disease. Patients with LVNC may face a higher risk of MI, potentially due to shared genetic factors.
Area of Science:
- Cardiology
- Genetics
Background:
- Left ventricular noncompaction (LVNC) is a rare congenital cardiomyopathy.
- The association between LVNC and ischemic heart disease remains incompletely understood.
Observation:
- A 73-year-old male with diagnosed LVNC presented with acute myocardial infarction (MI).
- The patient also had three-vessel coronary artery disease, an intraventricular thrombus, and mitral regurgitation.
Findings:
- The patient underwent successful treatment including anticoagulant therapy, coronary artery bypass grafting, and mitral valve repair.
- This case highlights a potential link between LVNC and MI/coronary artery disease.
Implications:
- Patients with LVNC may warrant closer monitoring for cardiovascular events like MI.
- Further research into a possible common genetic basis for LVNC and coronary artery disease is suggested.
Abstract:
We describe a 73-year-old male patient with left ventricular noncompaction (LVNC) who was diagnosed with acute myocardial infarction (MI), three-vessel coronary artery disease, a fresh intraventricular thrombus, and mitral regurgitation. He was treated with full anticoagulant therapy, coronary artery bypass grafting, and mitral valve repair. This case adds to a small but growing literature showing association between LVNC and MI and/or coronary artery disease. We suggest that patients with LVNC could be considered at heightened risk for MI, and the two conditions might have a common genetic underpinning in some cases.
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