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Related Concept Videos

Ethics and Bioethics01:22

Ethics and Bioethics

Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
What is Genetic Engineering?00:49

What is Genetic Engineering?

Overview
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...

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Updated: May 19, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

[Ethics and medical genetics].

Didier Lacombe1

  • 1Service de génétique Médicale, CHU de Bordeaux, Laboratoire "Maladies rares: Génétique et métabolisme", Université Bordeaux Segalen, Centre de Référence Anomalies du développement et syndromes malformatifs, 33076 Bordeaux.

Journal International De Bioethique = International Journal of Bioethics
|August 29, 2012
PubMed
Summary
This summary is machine-generated.

Medical genetics, focusing on ethical considerations, explores the implications of genetic testing, presymptomatic diagnosis, and bio-collections. The study reviews current bioethics laws to frame responsible practices in human genetics.

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FISH for Pre-implantation Genetic Diagnosis
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

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Last Updated: May 19, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Published on: January 16, 2019

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FISH for Pre-implantation Genetic Diagnosis

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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Area of Science:

  • Medical Genetics
  • Bioethics
  • Human Genomics

Context:

  • The family dimension distinguishes medical genetics.
  • Technological advancements in human genetics and genome research raise ethical questions.
  • Societal foundations and human standardization are challenged by human genetics.

Purpose:

  • To review the ethical issues surrounding genetic tests, presymptomatic, prenatal, and pre-implantation diagnosis, and bio-collections.
  • To examine the framework established by French bioethics laws for genetic practices.
  • To provide a current overview of ethical considerations in medical genetics.

Summary:

  • Genetic testing is a valuable medical tool requiring careful consideration of questions and expected results.
  • Bioethics laws in France provide a framework for practices in human genetics.
  • Ethical dilemmas span genetic testing, diagnosis, and bio-collections.

Impact:

  • Informs ethical guidelines for genetic testing and diagnosis.
  • Contributes to the responsible application of human genetics in medicine.
  • Supports the development of bioethics frameworks for emerging genetic technologies.