Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and range of geriatric medicine services across Europe: a survey of 39 countries.

European geriatric medicine·2026
Same author

Unraveling physical performance over time in hospitalized older patients with walking limitation: the role of ultrasound-derived vastus lateralis muscle thickness.

GeroScience·2026
Same author

Geriatric medicine across countries: Specialised workforce, training and system integration challenges.

The Journal of frailty & aging·2026
Same author

Exploring educational needs on frailty outside geriatrics: a survey of European Union of Medical Specialists' bodies.

European geriatric medicine·2026
Same author

Lessons learned from a multi-centre implementation of an artificial intelligence algorithm to detect vertebral fractures for radiology, information technology, information governance and clinical leads.

BJR artificial intelligence·2026
Same author

Mapping the landscape of geriatric medicine education, training and practice in Europe.

Age and ageing·2026

Related Experiment Video

Updated: May 19, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Handling knowledge on osteoporosis--a qualitative study.

Dorthe Nielsen1, Lotte Huniche, Kim Brixen

  • 1The Institute of Clinical Research, University of Southern Denmarik, Odense, Denmark. dnielsen@health.sdu.dk

Scandinavian Journal of Caring Sciences
|August 29, 2012
PubMed
Summary

Understanding osteoporosis is key for patients managing the condition daily. Life circumstances and attitudes toward treatment significantly impact how individuals handle osteoporosis, risk, and pain.

Keywords:
adherenceeveryday lifeknowledgeosteoporosispatient educationqualitative interviewsrisk

Related Experiment Videos

Last Updated: May 19, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Area of Science:

  • Medical Sociology
  • Health Psychology
  • Qualitative Health Research

Background:

  • Osteoporosis significantly impacts patients' daily lives and management strategies.
  • Understanding patient perspectives is crucial for effective osteoporosis care.
  • Existing research may not fully capture the nuances of living with osteoporosis.

Purpose of the Study:

  • To explore the importance of osteoporosis information and knowledge for patients.
  • To understand how patients manage osteoporosis in their everyday lives.
  • To investigate the influence of life conditions and treatment attitudes on osteoporosis management.

Main Methods:

  • Qualitative study employing semi-structured interviews.
  • 14 patients from English university hospitals and 12 from a Danish university hospital participated.
  • Critical psychology framework used for data analysis.

Main Results:

  • Life conditions significantly influence the handling of osteoporosis, risk perception, and pain.
  • Patients' attitudes toward treatment play a role in daily life management.
  • Emotional difficulties in managing osteoporosis were not solely linked to disease severity or fractures.

Conclusions:

  • Knowledge and information are vital for patients navigating life with osteoporosis.
  • Individual resourcefulness and past experiences shape responses to fracture risk.
  • A holistic approach considering life conditions and patient attitudes is essential for osteoporosis support.