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Identification of a new HLA-G allele, HLA-G*01:18, in a Canadian Caucasian individual

J Roger1, M-C Faucher, M Roger

  • 1Laboratoire d'immunogénétique, Centre de Recherche du Centre Hospitalier, Université de Montréal (CHUM), Montréal, Quebec, Canada.

Tissue Antigens
|August 29, 2012
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...