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The clinical picture of juvenile parotitis in a prospective setup
Riitta Saarinen1, Kaija-Leena Kolho, Irja Davidkin
1Department of Otorhinolaryngology and Head and Neck Surgery, Helsinki University, Helsinki, Finland. riitta.t.saarinen@hus.fi
Insights
Juvenile parotitis affects approximately 1% of children, typically presenting with mild symptoms and elevated serum amylase. Recurrent episodes occur in nearly half of cases, highlighting the need for further understanding of this condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Juvenile parotitis is a common childhood condition, but its clinical features and epidemiological characteristics require detailed characterization.
- Understanding the typical presentation and outcomes of juvenile parotitis is crucial for effective management and public health strategies.
Purpose of the Study:
- To prospectively characterize the clinical features, treatment, and outcomes of juvenile parotitis.
- To determine the epidemiology of juvenile parotitis in a defined population.
Main Methods:
- A prospective study of children with parotitis admitted to Helsinki University Central Hospital (2005-2010) was conducted.
- Clinical data, laboratory results (including serum amylase, C-reactive protein, leukocyte count), and SPINK-1 genotype were recorded.
- An epidemiological survey was distributed to 1000 randomly selected 13-year-old children.
Main Results:
- The study included 41 children with acute parotitis, all in good general condition.
- Elevated serum amylase was observed in 79% of cases, and C-reactive protein in 68%.
- Recurrent symptoms were reported in 46% of children, and the overall prevalence of parotitis was 1.1% based on the questionnaire.
Conclusions:
- Juvenile parotitis has an estimated frequency of approximately 1%.
- The majority of affected children maintain a good general condition during the illness.
- Serum amylase is a useful additional marker for diagnosing parotitis, which frequently recurs.
Aim:
To characterize the features of juvenile parotitis in a prospective setup and epidemiology.
Methods:
All children with parotitis admitted to Helsinki University Central Hospital 2005-2010 were recruited. Clinical characteristics, given treatment, outcome, blood leukocyte count, C-reactive protein, serum amylase and trypsinogen, SPINK-1 genotype and mumps antibodies were recorded. To map the epidemiology, a questionnaire was sent to 1000 randomly selected 13-year-old children.
Results:
The prospective study included 41 children (aged ≤ 17) with acute parotitis, all in good general condition. Serum amylase, but not trypsinogen, was elevated in majority of the cases (79%) and C-reactive protein in 68%. Eleven (27%) children had an elevated blood leukocyte count. None had acute mumps. Most children recovered well, 51% being treated symptomatically only. Seven children were treated on ward. Seventeen (46%) children had recurrent symptoms. One child (2.4%) had SPINK P55S mutation. According to the epidemiological questionnaire, 1.1% of the respondents (8/728, response rate 73%) reported a verified episode(s) of parotitis.
Conclusion:
Juvenile parotitis has a frequency close to 1%. In the majority, the general condition is good during the episode. Serum amylase serves as an additional marker for the disease. Parotitis has a tendency to recur in almost half of the cases.
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