Related Experiment Video
Updated: May 19, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
Anorectic and bulimic patients suffer from relevant sexual dysfunctions
Giovanni Castellini1, Lorenzo Lelli, Carolina Lo Sauro
1Department of Neurosciences, University of Florence, Florence, Italy.
Introduction:
Sexual life is often impaired in anorexia nervosa (AN) and bulimia nervosa (BN), and few studies have evaluated the possible relationships between body image concerns, eating disorder psychopathology, and sexual functioning in these syndromes.
Aim:
To evaluate sexual functioning in AN patients, BN patients, and healthy controls, and to define the predictors of sexual dysfunction in the AN and BN groups.
Methods:
Eighty-eight eating disorders patients (44 AN, 44 BN) referring to the Outpatient Clinic for Eating Disorders of the University of Florence, and 72 healthy females were evaluated.
Main Outcome Measures:
The subjects were studied by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders IV, the Female Sexual Function Index (FSFI), the Eating Disorder Examination Questionnaire, the Emotional Eating Scale, the Beck Depression Inventory, the Spielberg's State-Trait Anxiety Inventory, the Barratt Impulsiveness Scale, and the Symptom Checklist 90.
Results:
AN restricting/type patients had lower FSFI total scores (median; quartiles: 4.8; 2.1-15.4), compared with AN binge/purging type (28.3; 20.6-30.7) and BN patients (20.1; 3.8-30.3). Multiple linear regression analysis showed that shape concern was associated with sexual dysfunction in AN restricting type patients (β=-0.61, P<0.01), whereas emotional eating (β=-0.42, P<0.01), and subjective binge eating (β=-0.55, P<0.01) were significantly associated with FSFI scores in AN binge/purging type and BN patients.
Conclusions:
Considering the sample size, the present results must be considered as preliminary. Sexual dysfunction was found to be a relevant concern in both AN and BN patients and was associated with different pathological eating behaviors. Sexual functioning should be carefully investigated in eating disorders patients, and treatments focused on shape concern, emotional eating, and binge eating could improve the sexual life of AN and BN patients.
Related Concept Videos
Bulimia Nervosa
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Binge Eating Disorders
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists
Drugs for Treatment of Constipation-Predominant IBS

