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Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
The self-assembly and aqueous solubilization of [60]fullerene with disaccharides
Vinod I Bhoi1, S Kumar, C N Murthy
1Applied Chemistry Department, Faculty of Technology and Engineering, The MS University of Baroda, Vadodara, India.
Abstract:
Solubilization of [60]fullerene in water by complexation with disaccharides in mixed homogeneous solvent system, is described for the first time. The complexation of extremely water-insoluble [60]fullerene dissolved in non-polar solvent toluene and extremely water-soluble disaccharides dissolved in polar solvent DMSO resulted in an unique self-assembled highly crystalline water-soluble [60]fullerene-disaccharide complex. The interaction between [60]fullerene and disaccharides was found to be non-covalent and were characterized by FTIR, UV-Vis, NMR, XRD, and thermogravimetric analysis. The particle size of the lactose-C(60) complex was found to be monodisperse ~60 nm from Transmission Electron Microscopy (TEM) and matched with the size obtained from Static Light Scattering (SLS). Preliminary studies of radical scavenging on the most stable free radical 2,2'-diphenyl-1-picrylhydrazyl (DDPH) suggested that complex has potential biological applications.
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