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Updated: May 19, 2026
11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Alliance against MDRO: safeguarding antibiotics]
Annales Francaises D'Anesthesie Et De Reanimation
|August 29, 2012
Summary
Antibiotic resistance is a growing crisis with few new drugs available. An alliance of professionals and policymakers is urgently needed to combat multidrug-resistant organisms (MDROs).
Area of Science:
- Microbiology
- Public Health
- Pharmacology
Context:
- Escalating antibiotic resistance poses a significant threat to global health.
- The current pipeline for new antibiotics is critically insufficient to meet future demands.
- Existing treatments are failing for common infections, increasing risks for complex medical procedures.
Purpose:
- To highlight the urgent need for action against multidrug-resistant organisms (MDROs).
- To introduce a newly formed alliance dedicated to combating antibiotic resistance.
- To outline proposed measures and emphasize professional consensus.
Summary:
- Antibiotic resistance is dramatically increasing, with a severe shortage of new antibiotics expected.
- Excessive antibiotic use across human and animal sectors drives this resistance.
- An alliance involving healthcare professionals, consumers, managers, and politicians has formed to address MDROs.
Impact:
- Increased risk for surgeries, transplants, and immunosuppressive therapies.
- Potential for common infections to become untreatable.
- Urgent need for coordinated action and policy changes to preserve antibiotic efficacy.
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