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08:26
Nucleofection and In Vivo Propagation of Chicken Eimeria Parasites
Published on: February 14, 2020
Eimeria bovis: an update on parasite-host cell interactions.
Carlos Hermosilla1, Antonio Ruiz, Anja Taubert
1Institute of Parasitology, Justus Liebig University Giessen, Rudolf-Buchheim-Strasse 2, 35392 Giessen, Germany. Carlos.R.Hermosilla@vetmed.uni-giessen.de
International Journal of Medical Microbiology : IJMM
|August 29, 2012
Summary
Eimeria bovis, an apicomplexan parasite, extensively manipulates bovine endothelial cells for its prolonged development. This parasite exhibits a unique, lengthy intracellular merogony, requiring significant host cell modulation for survival.
Area of Science:
- Parasitology
- Cell Biology
- Host-Pathogen Interactions
Background:
- Apicomplexan parasites modulate host cells for survival.
- Toxoplasma gondii is a well-studied apicomplexan with broad host cell manipulation.
- Eimeria bovis merogony I is restricted to bovine endothelial cells.
Purpose of the Study:
- To review current data on Eimeria bovis-host cell interactions.
- To highlight E. bovis's capacity to exploit host cells.
Main Methods:
- Literature review of Eimeria bovis-host cell interactions.
Main Results:
- Eimeria bovis merogony I is host- and cell type-restricted.
- Intracellular E. bovis meront I development lasts up to 3 weeks.
- Macromeronts can reach 300 μm with 120,000 merozoites I.
Conclusions:
- Eimeria bovis requires intense host cell modulation for its unique development.
- This parasite demonstrates a significant capacity to exploit host cells for its benefit.
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