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Genital tuberculosis with variable presentation: a series of three cases
Rekha Sachan1, Munna Lal Patel, Pooja Gupta
1Department of Obstetrics and Gynaecology, CSM Medical University, Lucknow, Uttar Pradesh, India. drrekhasachan@gmail.com
BMJ Case Reports
|August 29, 2012
Summary
Genital tuberculosis (TB) presents variably, often mimicking other conditions. Newer diagnostic tests like TB PCR on endometrial tissue can detect secondary genital TB when cervical biopsies are inconclusive.
Area of Science:
- Reproductive Medicine
- Infectious Diseases
- Gynecologic Oncology
Background:
- Tuberculosis remains a significant global health challenge, particularly in developing regions.
- Genital tuberculosis is an underdiagnosed condition with diverse clinical manifestations.
Observation:
- Three cases of genital tuberculosis in women are presented with varied symptoms.
- Presentations included polymenorrhagia, postcoital bleeding, and cervical lesions.
- Histopathology confirmed tubercular cervicitis in one case.
Findings:
- Cervical biopsies were inconclusive for tuberculosis in two cases.
- Tuberculosis PCR on endometrial tissue was positive in these two cases, confirming secondary genital TB.
- This highlights the utility of molecular diagnostic markers.
Implications:
- Variable presentations of genital TB necessitate a high index of suspicion.
- Advanced diagnostic tools like PCR are crucial for accurate diagnosis of genital TB.
- Timely diagnosis and treatment are essential for managing genital tuberculosis and improving reproductive health outcomes.
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