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Related Concept Videos

Sensory Functions of the Skin01:16

Sensory Functions of the Skin

The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Introduction to the Integumentary System01:25

Introduction to the Integumentary System

The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...

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Sensitive skin: an overview.

E Berardesca1, M Farage, H Maibach

  • 1San Gallicano Dermatological Institute, VIa Chianesi 53, 00144, Rome, Italy. berardesca@berardesca.it

International Journal of Cosmetic Science
|August 30, 2012
PubMed
Summary
This summary is machine-generated.

Sensitive skin involves exaggerated reactions to everyday products and climate, often without visible irritation. Understanding its mechanisms, like barrier function and nerve pathways, is key to managing this common condition.

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Area of Science:

  • Dermatology
  • Cosmetic Science
  • Sensory Science

Background:

  • Sensitive skin is characterized by subjective hyper-reactivity to environmental factors and products.
  • Symptoms include itching, burning, stinging, and tightness, often without visible signs of irritation.
  • The condition is widespread but not fully understood, with potential links to constitutional factors and irritant exposure.

Purpose of the Study:

  • To explore the underlying mechanisms of sensitive skin.
  • To identify potential diagnostic markers for skin sensitivity.
  • To understand the role of the stratum corneum and neuronal pathways.

Main Methods:

  • Review of current literature on sensitive skin mechanisms.
  • Hypothesizing correlations with constitutional anomalies and occupational factors.
  • Investigating potential biological markers such as stratum corneum thickness, corneocyte size, and vanilloid receptor alterations.

Main Results:

  • Sensitive skin may involve a thinner stratum corneum, increasing penetration of chemicals.
  • Alterations in vanilloid receptors and neuronal transmission are implicated.
  • Monitoring skin barrier function, irritation potential, and sensory transmission can aid in identification.

Conclusions:

  • Sensitive skin arises from complex mechanisms, including barrier dysfunction and altered neurosensory pathways.
  • Further research is needed to fully define and diagnose sensitive skin.
  • Objective monitoring of skin parameters may help identify and manage sensitive skin conditions.