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Plasmacytoid dendritic cells control B cell-derived IL-10 production

Philipp Georg1, Isabelle Bekeredjian-Ding

  • 1Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, Heidelberg, Germany.

Autoimmunity
|August 30, 2012
PubMed
Summary

Plasmacytoid dendritic cells (pDCs) enhance B cell IL-10 production, crucial for immune tolerance. Direct pDC/B cell contact, not soluble factors, drives this suppressive mechanism.

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