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Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
How to diagnose and phenotype asthma
Parameswaran Nair1, Angira Dasgupta, Christopher E Brightling
1Department of Medicine, St Joseph's Healthcare, McMaster University, 50 Charlton Avenue East, Hamilton, Ontario L8N4A6, Canada. parames@mcmaster.ca
Abstract:
Asthma has been described as a chronic disease of the airways characterized by variable airflow obstruction, airway hyperresponsiveness, and airway inflammation. This review discusses the diagnosis and phenotyping of asthma, with a special emphasis on phenotyping based on the nature of cellular inflammation and radiological imaging and how this could be used to direct the treatment of asthma and, in the future, to apply specifically directed therapies to specific phenotypes.
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