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Clinical characteristics of rotavirus diarrhea in hospitalized Romanian infants

Gabriela Lesanu1, Cristina Adriana Becheanu, Raluca Maria Vlad

  • 1Department of Pediatrics, Grigore Alexandrescu Emergency Children's Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. glesanu@yahoo.com

The Pediatric Infectious Disease Journal
|August 30, 2012
PubMed

Insights

Rotavirus enteritis in infants (0-12 months) is common and often leads to severe illness. This study found rotavirus diarrhea caused significantly more severe disease compared to other causes of acute diarrhea.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Acute diarrhea is a leading cause of morbidity in infants.
  • Rotavirus is a common viral pathogen responsible for gastroenteritis worldwide.
  • Understanding the clinical severity of rotavirus in infants is crucial for effective management.

Purpose of the Study:

  • To compare the clinical characteristics of rotavirus enteritis with acute diarrhea from other etiologies in infants.
  • To determine the incidence and severity of rotavirus-associated diarrhea in a pediatric hospital setting.

Main Methods:

  • Retrospective review of medical records of children aged 0-12 months admitted with acute diarrhea.
  • Data collection included patient demographics, diagnosis, and disease severity.
  • Statistical analysis to compare rotavirus diarrhea with other diarrheal diseases.

Main Results:

  • A total of 839 infants were included in the study.
  • Rotavirus diarrhea accounted for 49.3% of all acute diarrhea cases.
  • Severe disease occurred in 65.2% of rotavirus cases, significantly higher than other etiologies (P < 0.01).

Conclusions:

  • Rotavirus is a significant cause of acute diarrhea in infants.
  • Rotavirus infection is associated with a higher incidence of severe disease compared to other causes of diarrhea in this age group.
  • Early identification and management of rotavirus gastroenteritis are essential for reducing severe outcomes in infants.

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