Quantitative characterization of growth rate of an incidental deep dermoid cyst in a child using sequential magnetic

Joshua H Hou1, Vinay K Aakalu, Pete Setabutr

  • 1Departments of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA. jhou.jhh@gmail.com

Insights

Deep orbital dermoid cysts, often found incidentally, may grow. This case study quantifies growth, suggesting close monitoring for these orbital lesions.

Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Radiology

Background:

  • Orbital lesions, particularly deep dermoid cysts, are often incidentally discovered.
  • Observation is sometimes recommended due to the perceived slow-growing nature of these tumors.

Observation:

  • A 7.5-month-old girl with retinoblastoma presented with an incidental deep orbital dermoid cyst.
  • The cyst was monitored using five sequential magnetic resonance imaging (MRI) scans over 23 months.
  • Quantitative measurements of the cyst's growth were carefully documented.

Findings:

  • The study provides the first published quantitative data on the growth potential of deep orbital dermoid cysts.
  • Histopathology confirmed the diagnosis of a dermoid cyst after surgical removal.
  • The case demonstrated measurable growth in the incidentally discovered orbital lesion.

Implications:

  • The findings challenge the assumption of consistently slow growth for deep orbital dermoid cysts.
  • Close early monitoring is crucial for incidentally discovered orbital lesions, even those presumed benign.
  • This case highlights the importance of serial imaging in evaluating the behavior of orbital tumors in pediatric patients.