Related Experiment Video
Updated: May 19, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
[Vascular grafts as access for hemodialysis]
1Klinik für Allgemein-, Viszeral- und Gefässchirurgie, Universitätsklinikum Jena, Erlanger Allee 101, 07743 Jena, Germany. juergen.zanow@med.uni-jena.de
Prosthetic arteriovenous grafts are secondary options for hemodialysis access when autogenous vessels fail. Careful planning and management ensure long-term function, making them essential in vascular access surgery.
Area of Science:
- Vascular Surgery
- Nephrology
- Biomaterials
Background:
- Prosthetic arteriovenous grafts (AVGs) offer an alternative vascular access for hemodialysis when autogenous options are unsuitable.
- AVGs are associated with lower patency rates and higher morbidity compared to autogenous fistulas.
- They are typically considered for secondary or tertiary access in patients with exhausted superficial arm veins.
Purpose of the Study:
- To review the indications for prosthetic arteriovenous grafts in hemodialysis.
- To discuss alternative configurations and characteristics of AVGs.
- To highlight the role of AVGs in contemporary vascular access surgery.
Main Methods:
- Literature review of studies on prosthetic arteriovenous grafts for hemodialysis access.
- Analysis of factors influencing AVG patency and morbidity.
- Comparison of AVGs with autogenous fistulas and tunnelled cuffed catheters.
Main Results:
- Prosthetic AVGs have inferior patency and greater morbidity than autogenous vessels.
- Careful pre-operative planning, surgical technique, and complication management are crucial for long-term AVG function.
- A variety of prosthetic conduits are available for AVG creation.
Conclusions:
- Arteriovenous grafts remain essential for hemodialysis vascular access, particularly in patients with complex venous anatomy or comorbidities.
- Their role may expand with increasing patient comorbidities.
- AVGs should be preferred over tunnelled cuffed catheters when feasible.
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