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Long-term outcomes after ROLL lumpectomy.

H S J Ramesh, S Anguille, S Poonawala

Indian Journal of Surgical Oncology

|August 30, 2012

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Radioactive-guided Occult Lesion Localization (ROLL) offers effective lumpectomy for early breast cancer. This technique demonstrates favorable long-term outcomes with a low local recurrence rate, comparable to other methods.

Area of Science:

Oncology
Surgical Oncology
Radiology

Background:

Radioactive-guided Occult Lesion Localization (ROLL) is a successful technique for targeting occult breast lesions.
ROLL enables the excision of non-palpable breast lesions with immediate benefits.

Purpose of the Study:

To evaluate the long-term outcomes of Radioactive-guided Occult Lesion Localization (ROLL) guided lumpectomy for early breast cancer.
Assessing local and/or systemic recurrence rates following ROLL procedures.

Main Methods:

A consecutive series of 151 patients with non-palpable early invasive breast cancers excised with ROLL between December 2002 and June 2006 were followed.
Follow-up included clinical examinations and imaging (mammogram, bone scan, liver, and brain imaging as needed).
Suspicious lesions for local recurrence were confirmed pathologically.

Keywords:

Breast cancer Local recurrence Localization Long-term outcomes Lumpectomy ROLL Radioisotopes Recurrence

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Main Results:

The median follow-up was 46 months, with a minimum of 22 months for all patients.
A total of 3 local recurrences were observed among 151 patients, resulting in a 1.98% local recurrence rate.

Conclusions:

Long-term outcomes, specifically local recurrence rates, for invasive breast cancer excised with ROLL guidance are comparable to existing localization techniques.
ROLL is a viable and effective method for the surgical management of early breast cancer.