Related Experiment Videos
A neuronal nicotinic acetylcholine receptor in crayfish neurons
1Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77251.
Neuroscience Letters
|December 11, 1990
Abstract:
In warm-blooded vertebrates, neuronal nicotinic acetylcholine receptors (nAChRs) are distinguished from muscle endplate receptors by their ligand affinities and sensitivity to several toxins. In the crayfish optic lobe, synaptic and acetylcholine (ACh)-elicited responses are blocked by toxins (F-toxin and neosurugatoxin) selective for neuronal nAChRs and are insensitive to the alpha-neurotoxins selective for endplate nAChRs.