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Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism I: Introduction01:29

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...

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Related Experiment Video

Updated: May 19, 2026

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
14:21

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Published on: January 22, 2013

Using optical coherence tomography to detect peripheral pulmonary thrombi.

Cheng Hong1, Wei Wang, Nan-Shan Zhong

  • 1Guangzhou Institute of Respiratory Diseases, State Key Laboratory of Respiratory Diseases, First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong 510120, China.

Chinese Medical Journal
|August 31, 2012
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) effectively detects peripheral pulmonary artery thrombi, differentiating red and white types. Follow-up OCT imaging confirmed thrombi reduction after anticoagulation treatment.

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Doppler Optical Coherence Tomography of Retinal Circulation
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Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Optical coherence tomography (OCT) provides high-resolution intravascular imaging.
  • OCT application in peripheral pulmonary arteries remains under-documented.

Observation:

  • Three patients with suspected peripheral pulmonary artery thrombi underwent OCT imaging.
  • CT pulmonary angiography was negative for thrombi in these patients.

Findings:

  • OCT identified thrombi in most imaged peripheral pulmonary arteries.
  • Red and white thrombi were distinguishable via OCT imaging.
  • Anticoagulation treatment led to symptom improvement and thrombi reduction/disappearance on repeat OCT.

Implications:

  • OCT shows potential for diagnosing peripheral pulmonary artery thrombi.
  • OCT may aid in differentiating thrombus types and monitoring treatment response.