Related Experiment Video
Updated: May 19, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
[Diabetes mellitus and osteoporosis. Bone metabolic disorder in diabetic nephropathy]
Shinsuke Yamada1, Masaaki Inaba
1Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan.
Abstract:
Life prognosis of hemodialysis patients with diabetes is remarkably bad compared with hemodialysis patients without diabetes. The major factor is existence of the specific bone metabolic disorder in patients with diabetes. Bone metabolic disorder is closely connected with vascular calcification, and it is thought that each disorder is induced by poor glycemic control. We will give an outline the influence which glycemic control has on bone metabolism and vascular calcification in hemodialysis patients with diabetes.
Related Concept Videos
Diabetic Nephropathy
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Chronic Kidney Disease II: Clinical Manifestations
Diabetic Neuropathy
Complications of Diabetes Mellitus
Type I Diabetes III: Clinical Manifestations
