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Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example
Published on: March 11, 2020
Multiple synchronous outbreaks of Puumala virus, Germany, 2010
Jakob Ettinger1, Jorg Hofmann, Martin Enders
1Charité Medical School and Labor Berlin Charité-Vivantes GmbH, Berlin, Germany.
Abstract:
To investigate 2,017 cases of hantavirus disease in Germany, we compared 38 new patient-derived Puumala virus RNA sequences identified in 2010 with bank vole-derived small segment RNA sequences. The epidemic process was driven by outbreaks of 6 Puumala virus clades comprising strains of human and vole origin. Each clade corresponded to a different outbreak region.
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