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Updated: May 19, 2026

Cerebral Ischemic Coma Model Induced by Modified Four-Vessel Occlusion
Published on: July 5, 2024
Emergency neurological life support: approach to the patient with coma
J Stephen Huff1, Robert D Stevens, Scott D Weingart
1Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA. jshuff505@me.com
Abstract:
Coma is an acute failure of neuronal systems governing arousal and awareness and represents a neurological emergency. When encountering a comatose patient, the clinician must have an organized approach to detect easily remedial causes, prevent ongoing neurologic injury, and determine a hierarchy of diagnostic tests, treatments, and neuromonitoring. Coma was chosen as an Emergency Neurological Life Support (ENLS) protocol because timely medical and surgical interventions can be life-saving, and the initial work-up of such patients is critical to establishing a correct diagnosis.
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