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Updated: May 19, 2026

Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

Published on: July 10, 2016

Microfluidics for manipulating cells.

Xuan Mu¹, Wenfu Zheng, Jiashu Sun

¹Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China.

Small (Weinheim an Der Bergstrasse, Germany)

|August 31, 2012

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Microfluidics offers precise cell manipulation for biology and medicine. This technology enables advanced cell analysis and interaction studies, with future clinical applications anticipated.

Area of Science:

Biotechnology
Cell Biology
Medical Devices

Background:

Microfluidics involves precise fluid manipulation at micro- to millimeter scales.
This technology is increasingly vital for cell manipulation in biological and medical research.

Purpose of the Study:

To review recent advancements in microfluidic cell manipulation.
To discuss current challenges and future prospects of microfluidics in cell biology and medicine.

Main Methods:

Utilizing microfluidic devices for cell handling.
Applying microfluidics for cell interaction management.
Employing microfluidics for high-throughput cell screening and single-cell analysis.

Main Results:

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Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

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A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

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A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

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Microfluidics provides novel perspectives for cell manipulation.

Demonstrated applications include dynamic cell interaction management and precise single-cell chemical analysis.

High-throughput screening of cells is facilitated by microfluidic systems.

Conclusions:

Microfluidics presents a powerful practical approach to address biological and medical needs involving cells.
The technology is expected to significantly advance the mechanistic understanding of cell biology.
Future roles in clinical applications are highly probable.