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Updated: May 19, 2026

Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
[One year evaluation of endodontic microsurgery in 54 cases with persistent apical periodontitis]
Jing Shen1, Haifeng Zhang, Shufeng Jin
1International Clinic Center, Affiliated Stomatological Hospital of Nankai University, Stomatological Hospital of Tianjin, Tianjin 300041, China.
Objective:
To evaluate the outcome of endodontic microsurgery in 54 cases with persistent apical periodontitis.
Methods:
All surgical procedures were performed under a dental operating microscope after root canal treatment. Surgical procedures included periapical curettage, root-end resection, retropreparation with ultrasonic microtips, and root-end filling with mineral trioxide aggregate (MTA). Healing was monitored clinically and radiographically.
Results:
One year later, 31 (57.41%) cases were cured, 19 (35.19%) cases were improved, 4 (7.41%) cases were failure. There were no statistical difference between sex, age, tooth location, size of the lesion and pathological features (P>0.05).
Conclusion:
The outcome of the present study indicates that endodontic microsurgery may result in a predictable treatment outcome in teeth with persistent periradicular lesions.
