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Updated: May 19, 2026

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index

Published on: March 28, 2025

[Sperm selection in assisted reproductive technology: an update].

Yue-Qiang Song¹, Yan-Wei Sha, Ping Li

¹Center of Reproductive Medicine, Xiamen Maternity and Child Health Care Hospital, Xiamen, Fujian 361003, China. songyueqiang@126.com

Zhonghua Nan Ke Xue = National Journal of Andrology

|September 1, 2012

Summary

This summary is machine-generated.

Advanced sperm selection techniques go beyond basic motility and morphology, incorporating DNA integrity and apoptosis for better outcomes in assisted reproduction. These methods aim to improve fertilization success rates in IVF and ICSI procedures.

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Area of Science:

Reproductive biology
Biotechnology
Medical diagnostics

Context:

Assisted reproductive technology (ART) relies heavily on effective sperm selection.
Traditional methods focus on motility and morphology, but newer approaches assess deeper sperm characteristics.
Sperm quality is crucial for successful fertilization and embryo development.

Purpose:

To provide an overview of novel sperm selection techniques.
To evaluate the advantages, disadvantages, and clinical applications of these advanced methods.
To highlight techniques beyond conventional sperm assessment.

Summary:

Explores advanced sperm selection methods including electrophoretic separation, zeta potential, hyaluronic acid (HA) binding, Annexin V binding, and intracytoplasmic morphologically selected sperm injection (IMSI).
Discusses the principles, benefits, limitations, and effectiveness of these techniques in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Introduces microfluidic sperm sorters as a developing technology for sperm separation.

Impact:

Enhances understanding of cutting-edge sperm selection technologies for ART.
Aims to improve sperm selection efficiency and success rates in fertility treatments.
Provides a comparative analysis to guide the choice of optimal sperm selection methods.