Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual-energy x-ray imaging for AI-based lung tumor localization using foundation models: a phantom study.

Physics in medicine and biology·2026
Same author

MRIgRT real-time target tracking: TrackRAD2025 challenge report.

Medical image analysis·2026
Same author

Microstructural modelling based on diffusion weighted imaging to guide dose painting in carbon ions for large sacral chordomas.

Physics and imaging in radiation oncology·2026
Same author

Microstructural profiling and habitat analysis to characterize treatment outcome patterns in Sacral Chordomas treated with carbon ions.

Medical physics·2025
Same author

GTV segmentation in MRI guided radiotherapy with promptable foundation models.

Physics in medicine and biology·2025
Same author

Generation of multimodal realistic computational phantoms as a test-bed for validating deep learning-based cross-modality synthesis techniques.

Medical & biological engineering & computing·2025

Related Experiment Video

Updated: May 7, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Real-time tumour tracking in particle therapy: technological developments and future perspectives.

Marco Riboldi1, Roberto Orecchia, Guido Baroni

  • 1Department of Bioengineering, Politecnico di Milano, Milan, Italy. marco.riboldi@polimi.it

The Lancet. Oncology
|September 1, 2012
PubMed
Summary

Accurate tumor tracking is crucial for radiation oncology, especially in particle therapy where motion impacts dose delivery. This review assesses real-time tumor localization strategies for improved cancer treatment.

More Related Videos

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Related Experiment Videos

Last Updated: May 7, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Area of Science:

  • Radiation oncology
  • Medical physics
  • Particle therapy

Background:

  • Accurate radiation dose delivery to moving tumors is a major challenge in radiation oncology.
  • Real-time tumor tracking and motion compensation are essential for precise radiotherapy.
  • Particle therapy, including proton and carbon-ion therapy, is highly sensitive to uncertainties in target localization due to beam characteristics.

Purpose of the Study:

  • To review and assess real-time tumor tracking strategies for particle therapy.
  • To compare different time-resolved target localization methods.
  • To evaluate the clinical outcomes of motion compensation techniques in particle therapy based on x-ray radiotherapy experience.

Main Methods:

  • Comparative analysis of existing tumor tracking and motion compensation techniques.
  • Assessment of target localization uncertainties in particle therapy.
  • Review of clinical outcomes related to motion management in radiation oncology.

Main Results:

  • Particle therapy requires stringent assessment of tumor localization uncertainties compared to x-ray radiotherapy.
  • Real-time tracking methods must be carefully evaluated for their efficacy in particle therapy.
  • Strategies for motion compensation in x-ray radiotherapy provide a basis for particle therapy applications.

Conclusions:

  • Real-time tumor tracking is critical for safe and effective particle therapy.
  • Performance assessment of localization and motion compensation methods is vital for clinical translation.
  • Further research is needed to optimize tumor tracking for particle therapy applications.