Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dose-response relationships in transcranial brain stimulation: Physics, physiology and mechanism.

Brain stimulation·2026

Same author

A double-blind replication attempt of offline 5Hz-rTUS-induced corticospinal excitability.

Imaging neuroscience (Cambridge, Mass.)·2025

Same author

The impact of brain lesions on tDCS-induced electric fields.

Scientific reports·2023

Same author

Individual placement and support focusing on employment and education for young people at clinical high risk of psychosis: A feasibility study.

Psychiatric rehabilitation journal·2023

Same author

Melvyn A. Goodale: A visual neuroscientist in action.

Neuropsychologia·2023

Same author

Patients with dorsal-stream lesions can perceive global shape.

Trends in cognitive sciences·2023

Search research articles

Related Experiment Video

Updated: May 19, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Published on: January 15, 2016

Optic ataxia affects the lower limbs: evidence from a single case study.

Carys Evans¹, A David Milner, Glyn W Humphreys

¹Department of Psychology, Durham University, Durham, UK.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior

|September 1, 2012

Summary

Optic ataxia, a spatial reaching deficit, affects lower limb movements, not just upper limbs. This suggests optic ataxia is not effector-specific and may impact visually guided locomotion.

More Related Videos

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Published on: March 21, 2019

Related Experiment Videos

Last Updated: May 19, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

Published on: January 15, 2016

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Efficiently Recording the Eye-Hand Coordination to Incoordination Spectrum

Published on: March 21, 2019

Area of Science:

Neuroscience
Cognitive Neuroscience
Visuomotor control

Background:

Optic ataxia is a spatial deficit in visually guided reaching due to parietal cortex damage.
Previous research focused on upper limb impairments, neglecting lower limb involvement.

Observation:

A patient with unilateral optic ataxia performed leg stepping tasks.
Performance was compared to age-matched controls under different viewing conditions.

Findings:

The patient exhibited significant errors in leg stepping accuracy, especially with the contralesional limb towards the periphery.
These deficits mirror previously observed upper limb impairments in optic ataxia.

Implications:

Optic ataxia is not strictly effector-specific, affecting both arms and legs.
Damage to the posterior parietal cortex impacts visuomotor transformations for multiple effectors.
Findings may explain locomotion difficulties in patients with optic ataxia.