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Related Concept Videos

Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Related Experiment Video

Updated: May 19, 2026

Microwave-driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis
08:13

Microwave-driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis

Published on: March 22, 2016

Progress in atherosclerotic plaque imaging.

Giulia Soloperto1, Sergio Casciaro

  • 1Giulia Soloperto, Sergio Casciaro, Biomedical Engineering Science and Technology Division and Nanoimaging Ultrasound Lab at National Research Council, Institute of Clinical Physiology (CNR-IFC), 73100 Lecce, Italy.

World Journal of Radiology
|September 1, 2012
PubMed
Summary

Identifying vulnerable atherosclerotic plaques is crucial for preventing heart attacks and strokes. This review explores advanced imaging techniques that go beyond traditional methods to detect unstable lesions, improving cardiovascular disease diagnosis.

Keywords:
AtherosclerosisDiagnostic imagingPlaque characterization

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Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis
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Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

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Microwave-driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis
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Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis
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Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

Area of Science:

  • Cardiovascular Medicine
  • Medical Imaging
  • Atherosclerosis Research

Background:

  • Cardiovascular diseases are a leading cause of death globally, primarily due to arterial obstruction from rupture-prone atherosclerotic plaques.
  • Conventional imaging methods often fail to identify vulnerable plaques as they may not cause flow-limiting stenosis.

Purpose of the Study:

  • To review current and emerging imaging modalities for assessing atherosclerotic plaque morphology and biology.
  • To highlight the diagnostic potential of various imaging techniques in identifying unstable atherosclerotic lesions.

Main Methods:

  • Discussion of ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), and nuclear imaging.
  • Inclusion of intravascular applications of these imaging modalities.
  • Review of clinically available and upcoming methodologies, considering invasiveness, accuracy, and cost-effectiveness.

Main Results:

  • Various imaging modalities offer specific diagnostic potential for characterizing atherosclerotic plaques.
  • Intravascular applications provide detailed insights into plaque features.
  • Emerging techniques present challenges in clinical translation regarding efficiency and cost.

Conclusions:

  • Advanced imaging techniques are essential for detecting vulnerable atherosclerotic plaques, which are critical for preventing myocardial infarction and cerebral stroke.
  • A comprehensive understanding of the capabilities and limitations of different imaging modalities is necessary for clinical application.
  • Further research is needed to overcome challenges in the clinical translation of novel imaging methods for atherosclerosis.