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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.

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Related Experiment Video

Updated: May 19, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Diffusion tensor imaging, structural connectivity, and schizophrenia.

Thomas J Whitford1, Marek Kubicki, Martha E Shenton

  • 1Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.

Schizophrenia Research and Treatment
|September 1, 2012
PubMed
Summary
This summary is machine-generated.

Schizophrenia may stem from disrupted brain communication, potentially linked to white matter abnormalities. Diffusion tensor imaging (DTI) reveals these structural changes, offering insights into the disorder's origins and progression.

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
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Related Experiment Videos

Last Updated: May 19, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
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Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Area of Science:

  • Neuroimaging
  • Psychiatric Disorders
  • Neuroscience

Background:

  • Schizophrenia is theorized to involve impaired communication between brain regions.
  • White matter tracts are crucial for long-range neural connectivity.
  • Abnormalities in white matter are implicated in schizophrenia's development.

Purpose of the Study:

  • To review the role of white matter abnormalities in schizophrenia.
  • To explain Diffusion Tensor Imaging (DTI) and its application in studying schizophrenia.
  • To explore the functional implications of white matter changes.

Main Methods:

  • Overview of Diffusion Tensor Imaging (DTI) principles.
  • Review of diffusion metrics used in neuroimaging.
  • Synthesis of existing literature on schizophrenia and white matter.

Main Results:

  • DTI visualizes in vivo white matter macrostructure.
  • Evidence suggests white matter abnormalities are present in schizophrenia.
  • Myelin's role in neural transmission velocity is considered.

Conclusions:

  • White matter abnormalities are a key area of study in schizophrenia.
  • DTI provides valuable insights into brain structure in schizophrenia.
  • A hypothesis on gray and white matter interactions in schizophrenia is proposed.