Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cervical ripening with mechanical method vs oral misoprostol in pregnancies with elevated BMI: a cohort study.

Archives of gynecology and obstetrics·2026
Same author

Comparing algorithm-tailored follitropin delta versus follitropin alpha dosing in expected poor responders: a cohort analysis.

Minerva obstetrics and gynecology·2026
Same author

The Impact of Thyroid Autoimmunity, Glucose Metabolism, and Vitamin D Status in Women With Recurrent Pregnancy Loss: A Retrospective Study.

Endocrine, metabolic & immune disorders drug targets·2026
Same author

Serum progesterone concentrations at frozen embryo transfer in women with adenomyosis and endometriosis: a retrospective cohort study.

Reproductive biology and endocrinology : RB&E·2026
Same author

Improving Midwifery Students' Communication and Counseling Skills in Maternal Nutrition: A Quality Improvement Educational Initiative.

Journal of midwifery & women's health·2026
Same author

T-shaped uterus metroplasty is associated with increased live birth rate in women with recurrent pregnancy loss: evidence form a matched case-control study.

Journal of minimally invasive gynecology·2026
Same journal

Autoinfarction of the Parathyroid Gland: An Unusual Presentation of Primary Hyperparathyroidism.

Case reports in endocrinology·2026
Same journal

Adrenal Tuberculosis Presenting as Adrenal Crisis: A Rare Presentation of Common Disease.

Case reports in endocrinology·2026
Same journal

Non-Autoimmune Hyperthyroidism Associated With a Novel Germline Mutation (D633N) in the TSH Receptor.

Case reports in endocrinology·2026
Same journal

Severe Osteoporosis in a Young Woman With Type 1 Diabetes and Pancreatic Exocrine Insufficiency.

Case reports in endocrinology·2026
Same journal

A Rare Case of Bartter Syndrome Type 3 Diagnosed in Elderly Age.

Case reports in endocrinology·2026
Same journal

Alternating Therapy With Osilodrostat and Etomidate in Severe Ectopic Cushing's Syndrome Complicated by Silent Bowel Perforation.

Case reports in endocrinology·2026
See all related articles

Related Experiment Video

Updated: May 19, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Severe hypothyroidism causing pre-eclampsia-like syndrome.

Annalisa Inversetti1, Audrey Serafini, Marco F Manzoni

  • 1Department of Obstetrics and Gynecology, San Raffaele Scientific Institute, Milan, Italy.

Case Reports in Endocrinology
|September 1, 2012
PubMed
Summary
This summary is machine-generated.

Severe hypothyroidism can mimic pre-eclampsia, leading to adverse pregnancy outcomes. Early recognition of this thyroid-related condition is crucial for appropriate management during pregnancy.

More Related Videos

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Related Experiment Videos

Last Updated: May 19, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Reproductive Medicine

Background:

  • Severe hypothyroidism, particularly Hashimoto's syndrome, can present with complex symptoms.
  • Pregnancy-induced hypertension and pre-eclampsia are common obstetric complications.

Observation:

  • A case of severe early-onset pre-eclampsia-like syndrome in a 42-year-old woman with severe hypothyroidism.
  • The patient experienced a miscarriage at 24 weeks of gestation despite treatment.

Findings:

  • Treatment with levothyroxine and liothyronine sodium did not prevent the adverse outcome.
  • The pre-eclampsia-like syndrome was attributed to overt hypothyroidism.

Implications:

  • Distinguishing hypothyroidism-induced pre-eclampsia-like syndrome from other hypertensive disorders is vital.
  • Accurate diagnosis is essential for selecting the correct therapeutic approach in pregnant patients.
  • This case highlights the importance of considering endocrine disorders in obstetric emergencies.