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Spermiogram part of population with the manifest orchitis during an ongoing epidemic of mumps
Belma Gazibera1, Refet Gojak, Alija Drnda
1Clinic for the Infectious Diseases, Clinical center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina. gazibera.belma@gmail.com
Introduction:
Incidence mumps infection has declined since the introduction of the inevitable MRP vaccination during the stage of childhood. In Bosnia and Herzegovina (BIH), from a period of February 2011 until today, there is an evident inclination of the recorded cases of the mumps infection. Orchitis usually occurs in between 3 to 10 days after the parotitis and is found with the post-puberty population.
Aim:
The aim of the study is to confirm the changes that occur during an early stage of the spermiogram and hormonal status, and after treated mumps orchitis, the patients treated in the Clinic for the Infectious Diseases.
Patients And Methods:
Retrospectively, the analysis of 54 historical diseases was undertaken. During the research stage, the patients after being discharged have made an inquiry to our clinical consultancy units with final results of the spermiogram and hormone-FSH, LH and testosteron. The data analysis was processed with the SPSS program for Windows.
Results:
the average length of the hospitalization period was in between 8 (medium) days, and average age M (mean) = 21,9 +/- 5,4 years. The speriogram of the treated patients was undertaken one month after the acute phase of the disease and has shown the following results: azoospermia with 14 patients (25,9%), oligospermia with 30 patients (55,6%) and normospermia with 10 patients (18,5%). During the hormonal status with 11 patients (20,4%), the results have shown the inclination of the value in FSH hormons, with 11 patients (20,4%), have shown the lesser value of the testosterons.
Conclusion:
The current study suggests that post-orhitis atrofia is expected within a period of 2-3 months after the infection, and thus, the monitoring on the patients' treatment would continue. The male infertility as a result of mumps ocrhitis is controversial and continues to be the thematic issue as well as the effect of orchitis on testicular endocrine function. Key words: epidemic, mumps
Insights
Mumps orchitis can lead to significant changes in semen quality and hormone levels in young men. Early monitoring of spermiogram and hormonal status is crucial for managing potential male infertility after mumps infection.
Area of Science:
- Infectious Diseases
- Andrology
- Endocrinology
Background:
- Mumps infection incidence has decreased due to childhood vaccination, but cases are increasing in Bosnia and Herzegovina.
- Mumps orchitis, inflammation of the testicles, typically affects post-pubertal males 3-10 days after parotitis (mumps of the salivary glands).
Purpose of the Study:
- To evaluate early changes in semen analysis (spermiogram) and hormone levels (FSH, LH, testosterone) in patients treated for mumps orchitis.
- To understand the impact of mumps orchitis on male reproductive health and endocrine function.
Main Methods:
- Retrospective analysis of 54 patient cases treated for mumps orchitis.
- Collection of spermiogram and hormone (FSH, LH, testosterone) data from patients during clinical consultancy after discharge.
- Statistical analysis of data using SPSS software.
Main Results:
- The average age of patients was 21.9 years, with an average hospitalization of 8 days.
- One month post-infection, spermiogram results showed: 25.9% azoospermia, 55.6% oligospermia, and 18.5% normospermia.
- Hormonal analysis revealed elevated FSH in 20.4% and decreased testosterone in 20.4% of patients.
Conclusions:
- Testicular atrophy is expected 2-3 months post-mumps orchitis, necessitating continued patient monitoring.
- The link between mumps orchitis and male infertility remains a subject of ongoing research and debate.
- Further investigation is needed to fully understand the effects of orchitis on testicular endocrine function.
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