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Updated: May 19, 2026
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Middle cerebral artery Doppler and hemoglobin changes immediately following fetal transfusion
Brendan H Grubbs1, Lisa M Korst, Arlyn Llanes
1Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.
Objective:
To determine the relationship between the change in middle cerebral artery peak systolic velocity (MCA-PSV) and the change in fetal Hemoglobin (Hb) immediately following intrauterine transfusion (IUT).
Materials And Methods:
Study data included all IUTs performed for suspected fetal anemia from 2007-2011.
Results:
Sixty-eight IUTs were performed for 23 pregnancies, demonstrating a statistically significant MCA-PSV decrease for up to four IUTs. Significant correlations between changes in Hb levels and MCA-PSV were not detected.
Conclusion:
MCA-PSV values were highly variable in the immediate post-operative period and did not correlate with the Hb change.
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