Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preparation, characterization and in vitro evaluation of atorvastatin nanosuspensions.

PloS one·2025
Same author

Deciphering angiotensin converting enzyme 2 (ACE2) inhibition dynamics: Carnosine's modulatory role in breast cancer proliferation - A clinical sciences perspective.

Heliyon·2024
Same author

Eco-friendly solvent bar microextraction based on a natural deep eutectic solvent and multivariate optimization for simultaneous determination of spironolactone and canrenone in urine and plasma samples.

Environmental science and pollution research international·2023
Same author

Community Pharmacy Practice During COVID-19 Pandemic: A Perspective From the Middle East.

Global journal on quality and safety in healthcare·2023
Same author

Cosmeceutical formulations of pro-vitamin E phosphate: In-vitro release testing and dermal penetration into excised human skin.

International journal of pharmaceutics·2023
Same author

Development of Dioctyl Phthalate@Fe<sub>3</sub>O<sub>4</sub> Nanocomposite Reinforced Hollow Fiber Solid/ Liquid Phase Microextraction Followed by HPLC-DAD for the Determination of Atorvastatin and Gemfibrozil in Human Urine.

Pharmaceutical nanotechnology·2021

Related Experiment Video

Updated: May 19, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes
07:49

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

Does massage postapplication improve moisturizer's efficacy? A 2-week regression study.

Saja H Hamed1, Intesar Assakir, Abdul-Majeed Almalty

  • 1Hashemite University, Zarqa, Jordan. hamedsh@hu.edu.jo

Journal of Cosmetic Dermatology
|September 4, 2012
PubMed
Summary
This summary is machine-generated.

Adding massage to moisturizer application did not significantly enhance its effectiveness for improving skin hydration, barrier function, or elasticity. The study found comparable skin improvements with or without massage after moisturizer use.

Related Experiment Videos

Last Updated: May 19, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes
07:49

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

Area of Science:

  • Dermatology
  • Cosmetic Science
  • Skin Physiology

Background:

  • Massage combined with moisturizer application is a popular spa treatment.
  • Subjective benefits are widely reported, but objective evidence is limited.
  • This study aimed to objectively assess massage's impact on moisturizer efficacy.

Purpose of the Study:

  • To objectively evaluate if local effleurage massage enhances moisturizer efficacy.
  • To determine the effect of massage post-moisturizer on skin barrier properties.
  • To compare skin hydration, barrier permeability, and elasticity with and without massage.

Main Methods:

  • A 2-week study with twice-daily moisturizer application on forearms.
  • One forearm received a 1-minute massage post-application; the other did not.
  • Skin barrier properties (TEWL, capacitance, elasticity) were measured noninvasively.

Main Results:

  • Both massage and no-massage groups showed similar improvements in skin hydration and barrier permeability.
  • These improvements were maintained after a 1-week regression period without treatment.
  • Skin elasticity also improved comparably in both application protocols.

Conclusions:

  • Daily massage after moisturizer application did not enhance the product's efficacy.
  • The study found no significant benefit of adding massage to moisturizer application for skin barrier improvement.
  • Objective measurements indicate massage is not a necessary adjunct for maximizing moisturizer benefits.