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Updated: May 19, 2026
08:14
Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
Published on: September 25, 2012
Infiltrative brainstem and cerebellar neurocytoma
Faiz Ahmad1, Marc K Rosenblum, Gabriel Chamyan
1Department of Neurological Surgery, University of Miami Miller School of Medicine and Miami Children's Hospital, USA.
Journal of Neurosurgery. Pediatrics
|September 4, 2012
Summary
Extraventricular neurocytomas are rare. This report details a unique case of a low-grade neurocytoma infiltrating the brainstem and cerebellum, managed conservatively with long-term success.
Area of Science:
- Neuro-oncology
- Pediatric neurosurgery
- Neuropathology
Background:
- Neurocytomas are typically intraventricular tumors, making extraventricular occurrences uncommon.
- Low-grade neurocytomas present unique challenges due to their infiltrative nature and potential for widespread dissemination.
Observation:
- A 15-year-old female presented with a rare extraventricular neurocytoma.
- The tumor infiltrated the brainstem and cerebellum, extending along cerebrospinal fluid (CSF) pathways to the lateral and third ventricles.
- Associated hydrocephalus necessitated endoscopic third ventriculostomy.
Findings:
- Biopsy confirmed a low-grade neurocytoma.
- The infiltrative and widespread nature precluded surgical resection and conventional radiation therapy.
- Conservative management with close follow-up was implemented.
Implications:
- This case highlights a previously unreported pattern of neurocytoma infiltration.
- Conservative management may be a viable option for select cases of unresectable, low-grade neurocytomas.
- Further research into optimal management strategies for extensive neurocytoma is warranted.
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