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Related Experiment Video

Updated: May 19, 2026

Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

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Age-dependent structural and radiological changes in the larynx.

Süha Türkmen¹, Aysegül Cansu, Süleyman Türedi

¹Department of Emergency Medicine, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey. drsuhaturkmen@hotmail.com

Clinical Radiology

|September 4, 2012

Summary

Radiological imaging reveals age-related changes in laryngeal anatomy, with ossification patterns in the thyroid cartilage and hyoid bone developing distinctly over decades. These findings establish a baseline for interpreting laryngeal radiographs in different age groups.

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Area of Science:

Radiology
Anatomy
Physiology

Background:

Laryngeal anatomy undergoes significant developmental changes throughout life.
Establishing an age-related radiological scale aids in accurate interpretation of cervical imaging.

Purpose of the Study:

To define age-related radiological and physiological changes in the larynx.
To establish an age-related scale for laryngeal ossification and tissue visibility.

Main Methods:

Retrospective analysis of lateral cervical radiographs from 300 patients.
Evaluation of thyroid cartilage and hyoid bone ossification and visibility.
Comparison of findings based on age and gender groups.

Main Results:

Thyroid and cricoid cartilage visibility emerged after the second decade.
Thyroid cartilage ossification progressed from posterior inferior to superior horns and lamina.
Hyoid bone ossification distinct in the first decade, fused by the third; it was the only ossified laryngeal structure below age 20.

Conclusions:

Age-specific radiological changes in laryngeal tissues are observable.
Radiologists and clinicians should consider these age-related patterns when assessing neck radiographs.