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Juvenile chronic myelogenous leukemia with abnormalities of chromosomes 4 and 5
S L Berg1, C K Phebus, S L Wenger
1Division of Hematology/Oncology, University of Pittsburgh, School of Medicine, Pennsylvania.
Cancer Genetics and Cytogenetics
|January 1, 1990
Abstract:
A case of a boy with juvenile chronic myelogenous leukemia (CML) and independent clonal abnormalities of chromosomes 4 and 5 is presented. The characteristics and cytogenetics of CML are discussed, as is the involvement of chromosomes 4 and 5 in hematologic malignancies. The significance of these karyotypic findings in juvenile CML is explored.