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Bronchiolitis outbreak caused by respiratory syncytial virus in southwest Bangladesh, 2010

Farhana Haque1, M Mushtuq Husain, Kazi Mohammad Hassan Ameen

  • 1Centre for Communicable Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh. farhanahaque@icddrb.org

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|September 4, 2012
PubMed

Insights

An outbreak of respiratory syncytial virus (RSV) bronchiolitis occurred in Bangladesh, affecting 101 children under two years old. Most cases were treated with antibiotics, highlighting the need for prevention strategies in low-income settings.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • A respiratory disease outbreak in southwestern Bangladesh led to numerous pediatric hospital admissions in July 2010.
  • Newspaper reports prompted an investigation into the outbreak's cause and risk factors.

Purpose of the Study:

  • To determine the etiology of the outbreak.
  • To identify risk factors associated with the respiratory illness in children.

Main Methods:

  • Reviewed hospital records of children under two years old diagnosed with acute bronchiolitis.
  • Collected nasal and throat swabs for respiratory virus testing.
  • Surveyed case patients to gather demographic and clinical information.

Main Results:

  • 101 acute bronchiolitis cases were identified, with a peak admission period between July 16-20.
  • Respiratory syncytial virus (RSV) was detected in 91% of tested samples, with 43% showing dual viral infections.
  • No deaths were reported, but 90% of patients received broad-spectrum antibiotics.

Conclusions:

  • The findings strongly suggest an outbreak of RSV bronchiolitis.
  • Prioritizing research for respiratory infection prevention, including RSV, in low-income settings is crucial.
  • Further exploration into the reasons for widespread antibiotic use in managing this viral syndrome is recommended.
Abstract

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