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Medical care costs of newly diagnosed children with structural-metabolic epilepsy: a one year prevalence-based
Muhannad R M Salih1, Mohd Baidi Bahari, Asrul Akmal Shafie
1College of Pharmacy, Al-Rashed University, Baghdad, Iraq. muhanad_rmk@yahoo.com
Insights
The first-year medical care costs for children with structural-metabolic epilepsy in Malaysia were MYR 202,816. Optimizing seizure control is key to reducing epilepsy management expenses.
Area of Science:
- Pediatric Neurology
- Health Economics
- Epileptology
Background:
- Epilepsy in children presents a significant healthcare burden.
- Understanding the economic impact of newly diagnosed epilepsy is crucial for resource allocation.
Purpose of the Study:
- To estimate the first-year medical care costs for children with structural-metabolic epilepsy.
- To identify key factors influencing these costs in Malaysia.
Main Methods:
- Retrospective chart review of pediatric neurology patients in a Malaysian tertiary referral center.
- Prevalence-based approach with bottom-up microcosting from a provider perspective.
- Standardized cost data for the year 2010.
Main Results:
- Total first-year costs were MYR 202,816 (MYR 1690.13 per patient).
- Antiepileptic drugs were the most significant cost driver, followed by hospitalization and non-antiepileptic drugs.
- Seizure frequency and antiepileptic drug type significantly predicted costs; demographic and other clinical variables did not.
Conclusions:
- This is the first cost analysis of childhood epilepsy in Malaysia.
- Effective seizure control strategies are essential for managing the economic burden of epilepsy.
- Further research into cost-effective treatment protocols is warranted.
Purpose:
Aims of this study were to estimate the first-year medical care costs of newly diagnosed children with structural-metabolic epilepsy and to determine the cost-driving factors in the selected population.
Method:
This was a prevalence-based retrospective chart review that included patients who attended a pediatric neurology clinic in a tertiary referral center in Malaysia. The total first-year medical care costs were estimated from the provider (i.e., hospital) perspective, using a bottom-up, microcosting analysis. Medical chart/billing data (i.e., case reports) obtained from the hospital (i.e., provider) were collected to determine the resources used. Prices or cost data were standardized for the year 2010 (One Malaysian Ringgit MYR is equivalent to 0.26 Euro or 0.32 USD).
Results:
The most expensive item in the costs list was antiepileptic drugs, whereas ultrasound examination represented the cheapest item. Hospitalization and the use of non-antiepileptic drugs were the second and third most costly items, respectively. The cost of therapeutic drug monitoring comprised only a small proportion of the total annual expenditure. None of the demographic variables (i.e., gender, race, and age) significantly impacted the first-year medical care costs. Similarly, child development, seizure type, therapy type (i.e., polytherapy versus monotherapy), and therapeutic drug monitoring utilization were also not associated with the cost of management. The first-year medical care costs positively correlated with seizure frequency (r(s)=0.294, p=0.001). However, the only variable that significantly predict the first-year medical care costs was the type of antiepileptic drugs (R(2)=0.292, F=7.772, p<0.001).
Conclusion:
This investigation was the first cost analysis study of epilepsy in Malaysia. The total first-year medical care costs for 120 patients with structural-metabolic epilepsy were MYR 202,816 (i.e., MYR 1690.13 per patient per year). The study findings highlight the importance of optimizing seizure control in reducing the cost of management.
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