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Updated: May 19, 2026
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
A nomogram for predicting lymph node metastasis of presumed stage I and II endometrial cancer
Sofiane Bendifallah1, Anne Sophie Genin, Iptissem Naoura
1Department of Obstetrics and Gynecology, Hospital Tenon, Assistance Publique-Hôpitaux de Paris, France.
Objective:
Our objective was to develop a nomogram based on pathological hysterectomy characteristics to provide a more individualized and accurate estimation of lymph node metastasis in endometrial cancer.
Study Design:
Data from the Surveillance, Epidemiology, and End Results database for 18,294 patients who underwent hysterectomy and lymphadenectomy were analyzed. A multivariate logistic regression analysis of selected prognostic features was performed, and a nomogram to predict lymph node metastasis was constructed. A cohort of 434 patients was used for the external validation.
Results:
The nomogram showed good discrimination with an area under the receiver operating characteristic curve of 0.80 (95% confidence interval, 0.79-0.81) in the training set and 0.79 (95% confidence interval, 0.78-0.80) in the validation set. The nomogram was well calibrated.
Conclusion:
We developed a nomogram based on 5 clinical and pathological characteristics to predict lymph node metastasis with a high concordance probability.
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