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A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research
Published on: July 31, 2017
Adenosine and autism: a spectrum of opportunities
Susan A Masino1, Masahito Kawamura, Jessica L Cote
1Neuroscience Program, Trinity College, 300 Summit St., Life Sciences Center, Hartford, CT 06106, USA. susan.masino@trincoll.edu
Abstract:
In rodents, insufficient adenosine produces behavioral and physiological symptoms consistent with several comorbidities of autism. In rodents and humans, stimuli postulated to increase adenosine can ameliorate these comorbidities. Because adenosine is a broad homeostatic regulator of cell function and nervous system activity, increasing adenosine's influence might be a new therapeutic target for autism with multiple beneficial effects. This article is part of the Special Issue entitled 'Neurodevelopmental Disorders'.
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