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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Hco-LGC-38 is novel nematode cys-loop GABA receptor subunit

Salma Z Siddiqui1, David D R Brown, Michael V Accardi

  • 1Applied Bioscience Graduate Program, University of Ontario Institute of Technology, Oshawa, Ontario, Canada.

Molecular and Biochemical Parasitology
|September 4, 2012
PubMed
Summary

Researchers identified a new GABA receptor subunit, Hco-LGC-38, in the parasitic nematode Haemonchus contortus. This discovery offers insights into nematode neurobiology and potential drug targets for parasitic infections.

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