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Published on: July 14, 2016
The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping
Steve D M Brown1, Mark W Moore
1MRC Mammalian Genetics Unit, MRC Harwell, Oxfordshire OX11 0RD, UK. s.brown@har.mrc.ac.uk
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Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.
