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Updated: May 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Deep vein thrombosis and septic pulmonary emboli with MRSA osteomyelitis in a pediatric patient
Rebecca Linn Schaub1, Mark Lee Rodkey
1Department of Pediatrics, Division of Pediatric Emergency Medicine, University of Texas Health Science Center at San Antonio, Christus Santa Rosa Children's Hospital, San Antonio, TX, USA.
Insights
Deep vein thrombosis (DVT) and pulmonary embolism (PE) are rare in children but serious. This case highlights a 5-year-old with DVT and PE caused by a bone infection, emphasizing the need for physician awareness.
Area of Science:
- Pediatric Medicine
- Infectious Diseases
- Hematology
Background:
- Deep vein thrombosis (DVT) and pulmonary embolism (PE) are uncommon in pediatric patients.
- Prompt diagnosis and treatment are crucial to prevent significant morbidity and mortality.
Observation:
- A 5-year-old boy presented to the emergency department with diagnosed DVT and PE.
- The underlying cause was identified as osteomyelitis of the left tibia.
- The infection was attributed to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA).
Findings:
- The patient experienced a prolonged hospital stay with multiple complications.
- Despite complications, the patient was ultimately discharged in good condition.
- Septic emboli from osteomyelitis can lead to DVT and PE.
Implications:
- Emergency department physicians must consider rare but severe complications of infections.
- Awareness of DVT and PE as potential sequelae of CA-MRSA osteomyelitis is vital.
- Early recognition and management are key in high-prevalence CA-MRSA areas.
Abstract:
Deep vein thrombosis (DVT) and pulmonary embolism (PE) are relatively rare occurrences in the pediatric population. However, DVT and PE are associated with significant morbidity and mortality to the patient if not promptly diagnosed and treated. We describe the case of a 5-year-old boy that was diagnosed in our emergency department with DVT and PE. The underlying etiology was osteomyelitis of the left tibia caused by community-acquired methicillin-resistant Staphylococcus aureus. The patient had a prolonged hospital course with multiple complications but was eventually discharged in a good condition. In areas with a high prevalence of community-acquired methicillin-resistant S. aureus, it is important for physicians in the emergency department to be aware of the rare, but potentially fatal, complications of infection, including DVT with PE from septic emboli.
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