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[Birth defects among children aged 0-4 in Chongqing in 2010]
Qiao Huang1, Zhao-hui Zhong, Jie Li
1Department of Epidemiology Research, College of Public Hygiene and Management of Chongqing Medical University, Chongqing 400016, China.
Insights
The study found a moderate prevalence of birth defects in Chongqing, China, affecting 33.48 per 1,000 children. Boys and children in rural areas exhibited higher rates of congenital anomalies compared to girls and urban children.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Context:
- Birth defects represent a significant global health concern, necessitating regional prevalence data for targeted interventions.
- Chongqing, a major municipality in China, requires updated epidemiological data on congenital anomalies to inform public health strategies.
Purpose:
- To determine the prevalence of birth defects among children aged 0-4 years in central economic districts of Chongqing.
- To identify specific types of birth defects and analyze demographic variations in their occurrence.
Summary:
- A multistage cluster sampling method surveyed 6,541 children aged 0-4 in Chongqing.
- The overall prevalence of birth defects was 33.48‰, with hernia and congenital heart disease being most common.
- Higher prevalence was observed in boys (52.99‰) and children from rural areas (40.17‰) compared to girls and urban children, respectively.
Impact:
- Findings indicate a moderate burden of birth defects in Chongqing, highlighting vulnerable populations.
- The data can guide the development of region-specific prevention and management programs for congenital anomalies.
- This study contributes essential epidemiological evidence for public health policy and resource allocation in Chongqing.
Objective:
To learn the prevalence of birth defects in Chongqing.
Methods:
A total of 6579 children aged 0 - 4 were chosen by multistage cluster sampling method in central economic districts of Chongqing. A total of 32 kinds of birth defects were selected. All the birth defects, except for the visible congenital malformation, must be diagnosed by the hospital in county. And municipal experts would make a consultation for those that couldn't be diagnosed at the level of county. Investigators trained strictly made a body examination and inquired medical history from May to September in 2010.
Results:
A total of 6541 subjects, aged from 0 to 4, were recruited in the present study, and 216 of them were born with birth defects. The total prevalence was 33.48‰ (95%CI: 29.09‰-37.87‰). There were 25 kinds of birth defects in total, the first five were hernia (20.15‰), congenital heart disease (2.17‰), polydactylism (2.02‰), cryptorchid (1.86‰) and funnel chest (1.86‰). The prevalence among boys was 52.99‰ (178/3359), higher than girls 12.29‰ (38/3092) (χ2=82.42, P<0.05). The prevalence in each group aged 0, 1, 2, 3, 4 were 39.30‰ (36/916), 38.79‰ (41/1057), 36.46‰ (56/1536), 28.38‰ (47/1656), 27.99‰ (36/1286), respectively. There were no statistical differences in each group (χ2=4.83, P=0.31). The prevalence in countryside was 40.17‰ (136/3386), higher than that in town 26.18‰ (80/3065) (χ2=9.83, P<0.05).
Conclusion:
The rate of birth defects in Chongqing was moderate, and boys and kids in rural areas had a higher prevalence rate than their counterparts.
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