Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasma microbial cell-free DNA sequencing for detection of <i>Coxiella burnetii</i> aortic endograft infection with vertebral osteomyelitis.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

Clinical utility of plasma microbial cell-free DNA sequencing for early diagnosis of toxoplasmosis in high-risk patients: a five-patient case series.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

Emergency department urine culture stewardship and downstream outcomes: a covariate-adjusted biweekly interrupted time series analysis.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis of <i>Tropheryma whipplei</i> by plasma microbial cell-free DNA.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

Candida auris screening positivity after discontinuation of cohort units and enhanced nursing engagement: An interrupted time series.

American journal of infection control·2026
Same author

Diagnosis of histoplasmosis by next-generation sequencing of microbial cell-free DNA in Texas.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026

Related Experiment Video

Updated: May 19, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
08:32

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

Staphylococcus aureus Bacteriuria: Source, Clinical Relevance, and Management.

Mayar Al Mohajer1, Rabih O Darouiche

  • 1Section of Infectious Diseases, Michael E. DeBakey VA Medical Center and Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA, mohajer@bcm.edu.

Current Infectious Disease Reports
|September 5, 2012
PubMed
Summary

Staphylococcus aureus bacteriuria is common but its clinical relevance is unclear. This review assesses its association with invasive diseases like endocarditis and guides management.

More Related Videos

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
07:10

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues

Published on: February 19, 2019

Establishment and Characterization of UTI and CAUTI in a Mouse Model
08:40

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

Related Experiment Videos

Last Updated: May 19, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
08:32

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
07:10

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues

Published on: February 19, 2019

Establishment and Characterization of UTI and CAUTI in a Mouse Model
08:40

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Urology

Background:

  • Staphylococcus aureus bacteriuria is frequently observed but its clinical significance remains poorly understood.
  • It can be a consequence of systemic infection or a precursor to invasive Staphylococcus aureus disease.
  • While often asymptomatic, it is linked to severe outcomes such as endocarditis, morbidity, and mortality.

Purpose of the Study:

  • To review and analyze existing literature on Staphylococcus aureus bacteriuria.
  • To evaluate the clinical relevance of Staphylococcus aureus bacteriuria.
  • To provide insights into the management of this condition.

Main Methods:

  • Systematic review and analysis of previous reports on Staphylococcus aureus bacteriuria.
  • Assessment of clinical outcomes and associations reported in the literature.
  • Synthesis of current evidence regarding diagnosis and treatment.

Main Results:

  • Staphylococcus aureus bacteriuria is associated with a significant risk of invasive Staphylococcus aureus infections.
  • Most cases do not present with symptomatic urinary tract infection.
  • The condition is linked to major morbidity and mortality, particularly from endocarditis.

Conclusions:

  • Staphylococcus aureus bacteriuria warrants careful consideration due to its association with invasive disease.
  • Further research is needed to clarify diagnostic criteria and optimal management strategies.
  • Early recognition and appropriate intervention may mitigate severe outcomes.