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Progress towards the synthesis of Urukthapelstatin A and two analogues
Chung-Mao Pan1, Chun-Chieh Lin, Seong Jong Kim
1Department of Chemistry and Biochemistry, 5500 Campanile Dr., San Diego State University, San Diego, CA 92182-1030 USA.
Tetrahedron Letters
|September 5, 2012
Abstract:
We report our progress towards the synthesis of Urukthapelstatin A (Ustat A) and two analogues. Our retrosynthetic strategy involved the synthesis of three fragments: a tri-heteroaromatic moiety, a phenyl oxazole fragment, and a dipeptide. Described are the syntheses of three unique tri-heteroaromatic moieties. In addition, the corresponding linear precursors of Ustat A and two analogues are presented.
