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Related Experiment Video

Updated: May 19, 2026

Operant Sensation Seeking in the Mouse
08:39

Operant Sensation Seeking in the Mouse

Published on: November 10, 2010

Centralized mouse repositories.

Leah Rae Donahue1, Martin Hrabe de Angelis, Michael Hagn

  • 1Mutant Mouse Regional Resource Center (MMRRC), The Jackson Laboratory, Bar Harbor, ME, USA. leahrae.donahue@jax.org

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|September 5, 2012
PubMed
Summary
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Centralized mouse repositories are crucial for preserving valuable mouse models used in biomedical research. These facilities ensure the ongoing availability of mouse strains, safeguarding research investments and creating a global resource.

Area of Science:

  • * Biomedical Research
  • * Genetics and Genomics
  • * Animal Models

Background:

  • * Mice are indispensable models in biomedical research, with a rapidly growing number of specialized strains and models being developed.
  • * The increasing complexity and quantity of mouse models necessitate secure preservation and efficient utilization strategies.
  • * Preserving these valuable genetic resources ensures the continuity of research and protects significant financial investments.

Purpose of the Study:

  • * To highlight the critical role of centralized repositories in the preservation and distribution of mouse models.
  • * To describe the essential functions and specialized services offered by global mouse repositories.
  • * To emphasize the value of these repositories as a global resource for the scientific community.

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Main Methods:

  • * Review of activities and services provided by major international mouse repositories.
  • * Analysis of common practices in archiving, distribution, and data management.
  • * Description of specialized services tailored to the needs of biomedical researchers.

Main Results:

  • * Centralized repositories provide essential infrastructure for the long-term storage and accessibility of mouse strains.
  • * Repositories offer a range of services including cryopreservation, breeding, phenotyping, and genetic analysis.
  • * These facilities facilitate the global sharing of mouse models, accelerating research and preventing duplication of effort.

Conclusions:

  • * Centralized mouse repositories are vital for the secure preservation and effective exploitation of valuable mouse models.
  • * The services offered by these repositories ensure the ongoing availability of critical research resources.
  • * Establishing and supporting global mouse repositories is essential for advancing biomedical research worldwide.